Karel Souček Selected Research

Toll-Like Receptor 3

1/2022	Toll-Like Receptor 3 Overexpression Induces Invasion of Prostate Cancer Cells, whereas Its Activation Triggers Apoptosis.
11/2020	Toll-Like Receptor 3 in Solid Cancer and Therapy Resistance.

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Karel Souček Research Topics

Disease

23	Neoplasms (Cancer) 05/2021 - 06/2011
7	Prostatic Neoplasms (Prostate Cancer) 01/2022 - 06/2011
6	Neoplasm Metastasis (Metastasis) 01/2022 - 03/2012
3	Carcinoma (Carcinomatosis) 10/2022 - 10/2011
3	Carcinogenesis 01/2021 - 10/2011
3	Breast Neoplasms (Breast Cancer) 01/2018 - 01/2012
2	Melanoma (Melanoma, Malignant) 10/2021 - 01/2018
2	Colonic Neoplasms (Colon Cancer) 10/2017 - 04/2013
2	Leukemia 01/2015 - 01/2013
1	Osteosarcoma (Osteogenic Sarcoma) 01/2022
1	Circulating Neoplastic Cells 05/2021
1	Lung Neoplasms (Lung Cancer) 01/2021
1	Triple Negative Breast Neoplasms 11/2020
1	Teratocarcinoma 01/2018
1	Polyploidy 10/2017
1	Genomic Instability 01/2017
1	Ovarian Neoplasms (Ovarian Cancer) 09/2015
1	Adenocarcinoma 05/2014
1	Myeloid Leukemia (Leukemia, Myelocytic) 01/2014
1	Colorectal Neoplasms (Colorectal Cancer) 04/2013
1	Prostatic Hyperplasia (Benign Prostatic Hyperplasia) 08/2012

Drug/Important Bio-Agent (IBA)

4	Transcription Factors (Transcription Factor)IBA 01/2022 - 01/2014
3	LigandsIBA 01/2021 - 10/2011
3	MK-8776IBA 10/2020 - 01/2017
3	Proteins (Proteins, Gene)FDA Link 01/2018 - 06/2011
3	DNA (Deoxyribonucleic Acid)IBA 10/2017 - 01/2014
2	Toll-Like Receptor 3IBA 01/2022 - 11/2020
2	MicroRNAs (MicroRNA)IBA 12/2021 - 10/2017
2	ElementsIBA 05/2021 - 01/2020
2	Aryl Hydrocarbon Receptors (Aryl Hydrocarbon Receptor)IBA 01/2021 - 10/2011
2	Polychlorinated Dibenzodioxins (TCDD)IBA 01/2021 - 08/2012
2	Pharmaceutical PreparationsIBA 11/2020 - 03/2018
2	CytokinesIBA 11/2020 - 04/2013
2	MU380IBA 10/2020 - 01/2017
2	FlavonoidsIBA 01/2015 - 01/2013
2	AndrogensIBA 05/2014 - 06/2011
1	Glycoproteins (Glycoprotein)IBA 10/2022
1	Benzo(a)pyreneIBA 01/2021
1	sacituzumab govitecanIBA 11/2020
1	InterferonsIBA 11/2020
1	Gemcitabine FDA Link 10/2020
1	Docetaxel (Taxotere)FDA Link 10/2020
1	salicylanilideIBA 05/2020
1	NaphtholsIBA 05/2020
1	Zinc Finger E-box-Binding Homeobox 1IBA 01/2020
1	Ubiquitin-Protein Ligases (Ubiquitin-Protein Ligase)IBA 01/2019
1	Hyaluronic Acid (Hyaluronan)IBA 10/2018
1	CypateIBA 10/2018
1	Contrast MediaIBA 10/2018
1	MicellesIBA 10/2018
1	Coloring Agents (Dyes)IBA 10/2018
1	hypericinIBA 03/2018
1	Epidermal Growth Factor (EGF)IBA 01/2018
1	EpitopesIBA 01/2018
1	Surface Antigens (Surface Antigen)IBA 01/2018
1	Epithelial Cell Adhesion MoleculeIBA 01/2018
1	Intercellular Signaling Peptides and Proteins (Growth Factors)IBA 01/2018
1	IntegrinsIBA 01/2018
1	A-factor (Streptomyces)IBA 01/2018
1	PlatinumIBA 10/2017
1	Drug CombinationsIBA 10/2017
1	Cisplatin (Platino)FDA LinkGeneric 10/2017
1	Checkpoint Kinase 1IBA 10/2017
1	Protein Serine-Threonine Kinases (Protein-Serine-Threonine Kinase)IBA 01/2017
1	Biomarkers (Surrogate Marker)IBA 09/2015
1	Antineoplastic Agents (Antineoplastics)IBA 01/2015
1	Transforming Growth Factors (Transforming Growth Factor)IBA 04/2013
1	Interleukin-11 (Interleukin 11)IBA 04/2013
1	cudraflavone BIBA 01/2013
1	LipopolysaccharidesIBA 01/2013
1	Cytochrome P-450 CYP1A1 (CYP1A1)IBA 08/2012
1	XenobioticsIBA 08/2012
1	EnzymesIBA 08/2012
1	Cathepsin DIBA 03/2012
1	Peptide Hydrolases (Proteases)FDA Link 03/2012
1	CollagenIBA 03/2012
1	Matrix Metalloproteinases (MMPs)IBA 03/2012
1	matrigelIBA 03/2012
1	rottlerinIBA 01/2012
1	MutagensIBA 10/2011
1	Polycyclic Aromatic Hydrocarbons (Polynuclear Aromatic Hydrocarbons)IBA 10/2011
1	Cathepsin BIBA 06/2011
1	VimentinIBA 06/2011
1	S-Phase Kinase-Associated Proteins (Skp1 Protein)IBA 06/2011
1	Androgen Receptors (Androgen Receptor)IBA 06/2011
1	GalactosidasesIBA 06/2011
1	Insulin-Like Growth Factor Binding Protein 3IBA 06/2011
1	HeterochromatinIBA 06/2011

Therapy/Procedure

12	Therapeutics 01/2022 - 06/2011
5	Drug Therapy (Chemotherapy) 11/2020 - 01/2012
3	Castration 01/2022 - 05/2014
1	Intravenous Administration 10/2018
1	Radiotherapy 01/2012